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Article

Partitioning Phenotypic Variance Due to Parent-of-Origin Effects Using Genomic Relatedness Matrices.

Behavior genetics - 1 Jan 2018

Laurin Charles, Cuellar-Partida Gabriel, Hemani Gibran, Smith George Davey, Yang Jian, Evans David M

Abstract excerpt

We propose a new method, G-REMLadp, to estimate the phenotypic variance explained by parent-of-origin effects (POEs) across the genome. Our method uses restricted maximum likelihood analysis of genome-wide genetic relatedness matrices based on individuals' phased genotypes. Genome-wide SNP data from parent child duos or trios is required to obtain relatedness matrices indexing the parental origin of offspring...

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Identifiers

PMID: 29098496
DOI: 10.1007/s10519-017-9880-0
PMCID: PMC5752821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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