Article

An integrated genome and phenome-wide association study approach to understanding Alzheimer’s disease predisposition

2022-01-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Genome-wide association studies (GWAS) have identified common, heritable alleles that increase late-onset Alzheimer’s disease (LOAD) risk. We recently published an analytic approach to integrate GWAS and phenome-wide association study (PheWAS) data, enabling identification of candidate traits and trait-associated variants impacting disease risk, and apply it here to LOAD. <h4>...

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Literature Corpus work: 60f92a83-ac6b-5e69-94fe-46c1a865bf7e
DOI: 10.1101/2022.01.03.22268705

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