Article
Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing
2018-04-04
Abstract excerpt
<h4>Introduction</h4> Late-onset Alzheimer’s disease (LOAD, onset age > 60 years) is the most prevalent dementia in the elderly 1 , and risk is partially driven by genetics 2 . Many of the loci responsible for this genetic risk were identified by genome-wide association studies (GWAS) 3–8 . To identify additional LOAD risk loci, the we performed the largest GWAS to date (89,769 individuals), analyzing both com...
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Identifiers and source
- Literature Corpus work
- ef213e10-99a8-5df4-96eb-9c734c640d50
- DOI
- 10.1101/294629