Article

Buffet-Style Expression Factor-Adjusted Discovery Increases the Yield of Robust Expression Quantitative Trait Loci

2015-10-11

Abstract excerpt

Expression quantitative trait locus (eQTL) analysis relates genetic variation to gene expression, and it has been shown that power to detect eQTLs is substantially increased by adjustment for measures of expression variability derived from singular value decomposition-based procedures (referred to as expression factors, or EFs). A potential downside to this approach is that power will be reduced for eQTL that are...

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Literature Corpus work: 609aaf00-025e-58a6-9dc1-75e870163308
DOI: 10.1101/028878

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