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Whole Genome DNA and RNA Sequencing of Whole Blood Elucidates the Genetic Architecture of Gene Expression Underlying a Wide Range of Diseases

2022-04-17

Abstract excerpt

<h4>ABSTRACT</h4> To create a scientific resource of expression quantitative trail loci (eQTL), we conducted a genome-wide association study (GWAS) using genotypes obtained from whole genome sequencing (WGS) of DNA and gene expression levels from RNA sequencing (RNA-seq) of whole blood in 2622 participants in Framingham Heart Study. We identified 6,778,286 cis -eQTL variant-gene transcript (eGene) pairs at p <5×10...

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Literature Corpus work: 5523bfd4-b2bd-546a-a37b-6fda7554652a
DOI: 10.1101/2022.04.13.22273841

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