Article

A Cell Type Enrichment Analysis Tool for Brain DNA Methylation Data (CEAM)

2025-07-11

Abstract excerpt

DNA methylation signatures are highly cell type-specific, yet most epigenome-wide association studies (EWAS) are performed on bulk tissue, potentially obscuring critical cell type-specific patterns. Existing computational tools for detecting cell type-specific DNAm changes are often limited by the accuracy of cell type deconvolution algorithms. Here, we introduce CEAM (Cell-type Enrichment Analysis for Methylation...

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Literature Corpus work: 60936003-b697-591a-aea6-5437d4ca1d66
DOI: 10.1101/2025.07.08.663671

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