Article

Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles

2023-06-23

Abstract excerpt

<h4>Background</h4> Due to inter-individual variation in the cellular composition of the human cortex, it is essential that covariates that capture these differences are included in epigenome-wide association studies using bulk tissue. As experimentally derived cell counts are often unavailable, computational solutions have been adopted to estimate the proportion of different cell-types using DNA methylation data...

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Literature Corpus work: 5213ea4e-163e-5ce6-ac21-e1c603961300
DOI: 10.1101/2023.06.23.545974

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