Article

Single-cell DNA methylation analysis tool Amethyst reveals distinct noncanonical methylation patterns in human glial cells

2024-08-16

Abstract excerpt

Single-cell sequencing technologies have revolutionized biomedical research by enabling deconvolution of cell type-specific properties in highly heterogeneous tissue. While robust tools have been developed to handle bioinformatic challenges posed by single-cell RNA and ATAC data, options for emergent modalities such as methylation are much more limited, impeding the utility of results. Here we present Amethyst, a...

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Literature Corpus work: 0cc1d5dd-8059-5510-a2b7-b3afc64041af
DOI: 10.1101/2024.08.13.607670

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