Article

Cell-type specific epigenetic links to schizophrenia risk in brain

2019-04-16

Abstract excerpt

The importance of cell-type specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuously lacking. We generated cell-type specific whole-genome methylomes ( N =95) and transcriptomes ( N =89) from neurons and oligodendrocytes from brains of schizophrenia and matched controls. The methylomes of these two cell-types are...

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Literature Corpus work: b3f5f40c-386f-5f35-81a8-e8d0849e5c46
DOI: 10.1101/609131

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