Article

SINEultaneous profiling of epigenetic heterogeneity and transcriptome in single cells

2021-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Global changes in DNA methylation are observed in developmental and disease contexts, and singlecell analyses are highlighting the heterogeneous regulation of these processes. However, technical challenges associated with single-cell analysis of DNA methylation limit these studies. We present single-cell transposable element methylation sequencing (scTEM-seq) for cost-effective estimation of glo...

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Literature Corpus work: 5f71189d-c5ed-56d8-a115-954c8329e4dc
DOI: 10.1101/2021.03.25.436351

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