Article

Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans

2025-10-21

Abstract excerpt

<h4>Summary: </h4> Humans exhibit significant phenotypic differences from other great apes, yet pinpointing the underlying genetic changes has been limited by incomplete reference genomes and a reliance on single assemblies to represent a species. We aligned 20 telomere-to-telomere (T2T) assemblies spanning great ape divergence and variation to define 1,596 Consensus HAQERs (consensus human ancestor quickly evolve...

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Literature Corpus work: cd9362b0-5bbd-5642-b240-c69201f37aca
DOI: 10.1101/2025.10.20.683446

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