Article

Loss of Carnitine Palmitoyltransferase 1a Reduces Docosahexaenoic Acid-Containing Phospholipids and Drives Sexually Dimorphic Liver Disease in Mice

2023-08-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Aims</h4> Genome and epigenome wide association studies identified variants in carnitine palmitoyltransferase 1a (CPT1a) that associate with lipid traits. The goal of this study was to determine the impact by which liver-specific CPT1a deletion impacts hepatic lipid metabolism. <h4>Approach and Results</h4> Six-to-eight-week old male and female liver-specific knockout (LKO)...

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Literature Corpus work: 5f0d5159-07d2-5e45-85d0-49fb19fc3a8b
DOI: 10.1101/2023.08.17.553705

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