Article

Hepatic Inactivation of Carnitine Palmitoyltransferase 1a Lowers Apolipoprotein B Containing Lipoproteins in Mice

2024-12-17

Abstract excerpt

<h4>SUMMARY</h4> Genome- and epigenome-wide association studies have associated variants and methylation status of carnitine palmitoyltransferase 1a (CPT1a) to reductions in very low-density lipoprotein (VLDL) cholesterol and triglyceride levels. We report significant associations between the presence of CPT1a SNPs and reductions in plasma cholesterol, as well as positive associations between hepatic Cpt1a expre...

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Literature Corpus work: 2a0669a6-e693-5c56-b51a-43b04c7588f7
DOI: 10.1101/2024.12.13.628437

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