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Article

Sex- and age-associated factors drive the pathophysiology of MASLD

26 Aug 2024

Abstract excerpt

BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly associated with obesity. Sex and age affect MASLD prevalence and pathophysiology. The use of animal models fed Western-style diets is vital for investigating the molecular mechanisms contributing to metabolic dysregulation and for facilitating novel drug target identification. However, the sex-associated and age-associated...

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PMID: 39185904
DOI: 10.1097/hc9.0000000000000523

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