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<i>yama</i> , a mutant allele of <i>Mov10l1</i> , disrupts retrotransposon silencing and piRNA biogenesis

2020-11-26

Abstract excerpt

Piwi-interacting RNAs (piRNAs) play critical roles in protecting germline genome integrity and promoting normal spermiogenic differentiation. In mammals, there are two populations of piRNAs: pre-pachytene and pachytene piRNAs. Transposon-rich pre-pachytene piRNAs are expressed in fetal and perinatal germ cells and are required for retrotransposon silencing, whereas transposon-poor pachytene piRNAs are expressed in...

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Literature Corpus work
577ce2c3-a80e-5153-b627-11bbaf60245e
DOI
10.1101/2020.11.26.399659
Open publication

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<i>yama</i> , a mutant allele of <i>Mov10l1</i> , disrupts retrotransposon silencing and piRNA biogenesisDOI 10.1101/2020.11.26.399659
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