Article

PIWIL3-piRNA Pathway Is Essential for Rabbit Oogenesis and Embryogenesis via Broad Regulation of the Transcriptome and Proteome

2025-10-24

Abstract excerpt

<h4>ABSTRACT</h4> Female infertility represents a significant challenge in reproductive medicine. Although it is known to be primarily due to oogenic and early embryonic failures, the molecular mechanisms underlying these failures remain elusive. The Piwi-piRNA pathway is crucial for gametogenesis in diverse organisms. Yet, its role in mammalian female fertility is unclear. This is partly because most studies are...

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Literature Corpus work: ad084ee2-fd68-5525-b544-cb0e8c472ed6
DOI: 10.1101/2025.10.23.684072

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