Article

Comparative chromatin accessibility upon BDNF-induced neuronal activity delineates neuronal regulatory elements

2021-05-28

Abstract excerpt

Neuronal activity induced by brain-derived neurotrophic factor (BDNF) triggers gene expression, which is crucial for neuronal survival, differentiation, synaptic plasticity, memory formation, and neurocognitive health. However, its role in chromatin regulation is unclear. Here, using temporal profiling of chromatin accessibility and transcription in mouse primary cortical neurons upon either BDNF stimulation or de...

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Literature Corpus work: 5e1984d6-a866-55da-94fc-10f47f37e1ac
DOI: 10.1101/2021.05.28.446128

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