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Article

Enhancer Dynamics and Spatial Organization Drive Anatomically Restricted Cellular States in the Human Spinal Cord

2025-01-11

Abstract excerpt

<h4>SUMMARY</h4> Here, we report the spatial organization of RNA transcription and associated enhancer dynamics in the human spinal cord at single-cell and single-molecule resolution. We expand traditional multiomic measurements to reveal epigenetically poised and bivalent active transcriptional enhancer states that define cell type specification. Simultaneous detection of chromatin accessibility and histone modi...

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Literature Corpus work
628be1b8-e014-52bc-b05c-494c8e02023b
DOI
10.1101/2025.01.10.632483
Open publication

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Enhancer Dynamics and Spatial Organization Drive Anatomically Restricted Cellular States in the Human Spinal CordDOI 10.1101/2025.01.10.632483
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