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Article

A Chromatin Accessibility Atlas of the Developing Human Telencephalon.

Cell - 6 Aug 2020

Markenscoff-Papadimitriou Eirene, Whalen Sean, Przytycki Pawel, Thomas Reuben, Binyameen Fadya, Nowakowski Tomasz J, Kriegstein Arnold R, Sanders Stephan J, State Matthew W, Pollard Katherine S, Rubenstein John L

Abstract excerpt

To discover regulatory elements driving the specificity of gene expression in different cell types and regions of the developing human brain, we generated an atlas of open chromatin from nine dissected regions of the mid-gestation human telencephalon, as well as microdissected upper and deep layers of the prefrontal cortex. We identified a subset of open chromatin regions (OCRs), termed predicted regulatory...

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Identifiers

PMID: 32610082
DOI: 10.1016/j.cell.2020.06.002
PMCID: PMC7415678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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