Article

Human hippocampus niche and circuit neurotypical and major depression profiles

2026-01-16

Abstract excerpt

<title>Abstract</title> <p> Hippocampal neuroplasticity regulates memory and emotional responses, which are altered in major depression, a leading cause of disability worldwide <sup>1</sup> . Molecular underpinnings of reduced hippocampal neuroplasticity <sup>2</sup> , fewer neurons, and smaller volume <sup>3,4</sup> in MDD are unknown and may involve blunted adult hippocampal neurogenesis (AHN), a debated...

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Literature Corpus work: caa38ce4-ccfb-519f-a36f-479ca142911f
DOI: 10.21203/rs.3.rs-8593764/v1

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