Article

Evaluation of Chromatin Accessibility in Prefrontal Cortex of Schizophrenia Cases and Controls

2017-05-25

Abstract excerpt

Schizophrenia genome-wide association (GWA) studies have identified over 150 regions of the genome that are associated with disease risk, yet there is little evidence that coding mutations contribute to this disorder. To explore the mechanism of non-coding regulatory elements in schizophrenia, we performed ATAC-seq on adult prefrontal cortex brain samples from 135 individuals with schizophrenia and 137 controls, a...

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Literature Corpus work: 5d45f968-0a77-5bf1-9e82-f94b59bcbe40
DOI: 10.1101/141986

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