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Article

Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.

Human molecular genetics - 15 May 2017

Fullard John F, Giambartolomei Claudia, Hauberg Mads E, Xu Ke, Voloudakis Georgios, Shao Zhiping, Bare Christopher, Dudley Joel T, Mattheisen Manuel, Robakis Nikolaos K, Haroutunian Vahram, Roussos Panos

Abstract excerpt

Open chromatin provides access to DNA-binding proteins for the correct spatiotemporal regulation of gene expression. Mapping chromatin accessibility has been widely used to identify the location of cis regulatory elements (CREs) including promoters and enhancers. CREs show tissue- and cell-type specificity and disease-associated variants are often enriched for CREs in the tissues and cells that pertain to a given...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28335009
DOI: 10.1093/hmg/ddx103
PMCID: PMC6059160

Genes

SNX19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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