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Article

Active field theory approach to explain size control of transcriptional condensates

2026-05-20

Abstract excerpt

Transcription factors organize into liquid-like condensates to facilitate gene expression, yet the physical mechanisms governing their formation and properties remain poorly understood. We study the size statistics of transcriptional condensates in human HAP1 cells using widefield and super-resolution microscopy tagging the epigenetic reader BRD4. We find that hubs that appear monolithic in widefield resolve into...

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Literature Corpus work
5d135bb7-29f7-5680-86bc-f0be22ef705b
DOI
10.64898/2026.05.17.725716
Open publication

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Active field theory approach to explain size control of transcriptional condensatesDOI 10.64898/2026.05.17.725716
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