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Article

Biomolecular Condensates Decipher Molecular Codes of Cell Fate: From Biophysical Fundamentals to Therapeutic Practices.

International journal of molecular sciences - 8 Apr 2024

Sun Xing, Zhou Yangyang, Wang Zhiyan, Peng Menglan, Wei Xianhua, Xie Yifang, Wen Chengcai, Liu Jing, Ye Mao

Abstract excerpt

Cell fate is precisely modulated by complex but well-tuned molecular signaling networks, whose spatial and temporal dysregulation commonly leads to hazardous diseases. Biomolecular condensates (BCs), as a newly emerging type of biophysical assemblies, decipher the molecular codes bridging molecular behaviors, signaling axes, and clinical prognosis. Particularly, physical traits of BCs play an important role;...

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PMID: 38612940
DOI: 10.3390/ijms25074127
PMCID: PMC11012904

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