Article

Using <i>de novo</i> assembly to identify structural variation of complex immune system gene regions

2021-02-04

Abstract excerpt

Driven by the necessity to survive environmental pathogens, the human immune system has evolved exceptional diversity and plasticity, to which several factors contribute including inheritable structural polymorphism of the underlying genes. Characterizing this variation is challenging due to the complexity of these loci, which contain extensive regions of paralogy, segmental duplication and high copy-number repeat...

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Literature Corpus work: 5d0b10c8-7f77-5f63-87e7-cbd15e361418
DOI: 10.1101/2021.02.03.429586

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