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Article

Genetic complexity of killer-cell immunoglobulin-like receptor genes in human pangenome assemblies.

Genome research - 20 Sept 2024

Hung Tsung-Kai, Liu Wan-Chi, Lai Sheng-Kai, Chuang Hui-Wen, Lee Yi-Che, Lin Hong-Ye, Hsu Chia-Lang, Chen Chien-Yu, Yang Ya-Chien, Hsu Jacob Shujui, Chen Pei-Lung

Abstract excerpt

The killer-cell immunoglobulin-like receptor (KIR) gene complex, a highly polymorphic region of the human genome that encodes proteins involved in immune responses, poses strong challenges in genotyping owing to its remarkable genetic diversity and structural intricacy. Accurate analysis of KIR alleles, including their structural variations, is crucial for understanding their roles in various immune responses....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39251346
DOI: 10.1101/gr.278358.123
PMCID: PMC11444179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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