Article
A Database of Human Immune Receptor Alleles Recovered from Population Sequencing Data.
Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 2017
Yu Yaxuan, Ceredig Rhodri, Seoighe Cathal
Abstract excerpt
High-throughput sequencing data from TCRs and Igs can provide valuable insights into the adaptive immune response, but bioinformatics pipelines for analysis of these data are constrained by the availability of accurate and comprehensive repositories of TCR and Ig alleles. We have created an analytical pipeline to recover immune receptor alleles from genome sequencing data. Applying this pipeline to data from the...
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