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Article

Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures.

HLA - 1 Jul 2023

Houwaart Torsten, Scholz Stephan, Pollock Nicholas R, Palmer William H, Kichula Katherine M, Strelow Daniel, Le Duyen B, Belick Dana, Hülse Lisanna, Lautwein Tobias, Wachtmeister Thorsten, Wollenweber Tassilo E, Henrich Birgit, Köhrer Karl, Parham Peter, Guethlein Lisbeth A, Norman Paul J, Dilthey Alexander T

Abstract excerpt

Accurate and comprehensive immunogenetic reference panels are key to the successful implementation of population-scale immunogenomics. The 5Mbp Major Histocompatibility Complex (MHC) is the most polymorphic region of the human genome and associated with multiple immune-mediated diseases, transplant matching and therapy responses. Analysis of MHC genetic variation is severely complicated by complex patterns of...

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Identifiers

PMID: 36932816
DOI: 10.1111/tan.15020
PMCID: PMC10986641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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