Article

Genomics reveals eleven obesity endotypes with distinct biological and phenotypic signatures

2025-07-01

Abstract excerpt

Obesity, a leading global risk factor for cardiometabolic conditions, arises from multifaceted and biologically complex mechanisms 1,2 . To elucidate the full-dimensional genetic architecture underlying obesity, we conducted a multi-trait, multi-ancestry, genome-wide association study (GWAS) by combining genetic data on anthropometric traits (body mass index, waist circumference, waist-to-hip ratio, and hip circu...

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Literature Corpus work: 5cf6d64f-7fba-539d-8ff7-1568158f9e84
DOI: 10.1101/2025.06.30.25330607

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