Article

Clustering of Type 2 Diabetes Genetic Loci by Multi-Trait Associations Identifies Disease Mechanisms and Subtypes

2018-05-10

Abstract excerpt

<h4>Background</h4> Type 2 diabetes (T2D) is a heterogeneous disease for which 1) disease-causing pathways are incompletely understood and 2) sub-classification may improve patient management. Unlike other biomarkers, germline genetic markers do not change with disease progression or treatment. In this paper we test whether a germline genetic approach informed by physiology can be used to deconstruct T2D heteroge...

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Literature Corpus work: 82075a7e-a299-5a6d-8e39-268bc930a014
DOI: 10.1101/319509

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