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Distinct T cell chromatin landscapes in circulating lymphocytes from patients with systemic sclerosis

2021-01-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Systemic sclerosis (SSc; scleroderma) disproportionately affects biological females, and results of multiple studies implicate lymphocyte derangements in disease pathogenesis supporting use of mycophenolate mofetil (MMF) treatment. Here, we surveyed chromatin accessibility of circulating CD4+ T lymphocytes from SSc patients commencing MMF to gain molecular insights into syst...

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Literature Corpus work
5cdbc9a4-3af7-574e-8257-66f0f6f9323f
DOI
10.1101/2021.01.10.426131
Open publication

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Distinct T cell chromatin landscapes in circulating lymphocytes from patients with systemic sclerosisDOI 10.1101/2021.01.10.426131
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