Article

Transcriptional landscape of CD4+ T cells in Systemic Sclerosis

2026-01-03

Abstract excerpt

<h4>Objective</h4> This resource deeply characterizes the CD4+ T cell subpopulations populations in SSc patients, with a novel single-cell RNA sequencing (scRNA-seq) approach, offering unprecedented insights into the cellular and molecular underpinnings of the disease. <h4>Methods</h4> We performed scRNA-seq to analyze over 80,000 CD4+ T cells from 8 SSc patients and 8 healthy controls, integrating abundance, tr...

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Literature Corpus work: 4e2310ba-0eff-5da0-a9cf-c9730766c3ca
DOI: 10.64898/2026.01.03.697349

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