Integrated single-cell chromatin and transcriptomic analyses of peripheral immune cells in patients with alopecia areata

Abstract excerpt

Introduction Alopecia areata (AA) is an autoimmune disorder characterized by non-scarring hair loss ranging from mild, self-limiting episodes to severe and chronic forms. While prior research has primarily focused on lesional skin, the contribution of systemic immune cells remains underexplored. Methods We performed integrated single-cell RNA sequencing (scRNA-seq) and single-cell assay for transposase-accessible...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hair Growth and Disorders
• Share to Mast cells and histamine
• Share to Mesenchymal stem cell research