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Article

The altered T cell landscape in Systemic Sclerosis patients is characterized by dysfunctional type 1 immunity

2025-12-13

Abstract excerpt

<h4>Background</h4> T cells in patients with chronic autoimmunity show features of dysfunction and exhaustion. However, the functionally-defined T cell subsets affected by these changes remain poorly characterized. Here, we sought to reveal aberrations in the composition, phenotype and function of canonical T cell subsets in the blood of Systemic Sclerosis (SSc) patients, compared to healthy subjects and Systemic...

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Identifiers and source

Literature Corpus work
28986524-115a-5b9e-8759-89959b1563c9
DOI
10.64898/2025.12.10.693457
Open publication

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