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The genomic and transcriptional landscape of the spinal cord H3K27-altered diffuse midline glioma suggests the potential therapeutic strategy

2025-05-29

Abstract excerpt

Diffuse midline glioma with H3K27-altered (DMG) is a lethal pediatric malignancy that primarily occurs in the brainstem of children. In adults, DMG arising in the spinal cord is rarely reported and remains poorly understood. The cellular architecture and clinical outcomes of DMG vary depending on the tumor’s location. To dissect the genomic and transcriptional architecture of a cohort of spinal cord DMG patients,...

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Literature Corpus work
5ca24638-a6b9-53d0-9843-1ecc2ccd1fce
DOI
10.1101/2025.05.25.655886
Open publication

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The genomic and transcriptional landscape of the spinal cord H3K27-altered diffuse midline glioma suggests the potential therapeutic strategyDOI 10.1101/2025.05.25.655886
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