Article
Genomic profiling and prognostic factors of H3 K27M-mutant spinal cord diffuse glioma.
Brain pathology (Zurich, Switzerland) - 1 Jul 2023
Chai Rui-Chao, Yan Hao, An Song-Yuan, Pang Bo, Chen Hui-Yuan, Mu Quan-Hua, Zhang Ke-Nan, Zhang Yao-Wu, Liu Yu-Qing, Liu Xing, Zhao Zheng, Jiang Tao, Wang Yong-Zhi, Jia Wen-Qing
Abstract excerpt
H3 K27-altered diffuse midline glioma is a highly lethal pediatric-type tumor without efficacious treatments. Recent findings have highlighted the heterogeneity among diffuse midline gliomas with different locations and ages. Compared to tumors located in the brain stem and thalamus, the molecular and clinicopathological features of H3 K27-altered spinal cord glioma are still largely elusive, thus hindering the...
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