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Article

Survival analysis of adult midline-located gliomas and diffuse midline gliomas: beyond the H3K27 mutation paradigm.

Journal of neuro-oncology - 22 May 2026

Jung In-Ho, Yoo Jihwan, Choi Seonah, Roh Tae Hoon, Park Hun Ho, Lim Jaejoon, Moon Ju Hyung, Kim Eui Hyun, Kang Seok-Gu, Kim Se Hoon, Chang Jong Hee

Abstract excerpt

PURPOSE: Although pediatric midline-located gliomas (MGs) with H3K27 alteration have been widely known to have a poor prognosis, few researchers have assessed adult MGs with H3K27 alteration. We aimed to determine the effect of H3K27 alteration on the prognosis of adult MGs. And we tried to identify the factors affecting the prognosis of diffuse midline glioma (DMG). This is the first study to investigate the...

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PMID: 42174302
DOI: 10.1007/s11060-026-05625-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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