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Construction of a complete set of <i>Neisseria meningitidis</i> defined mutants – the NeMeSys 2.0 collection – and its use for the phenotypic profiling of the genome of an important human pathogen

2020-08-12

Abstract excerpt

One of the great challenges in biology is to determine the function of millions of genes of unknown function. Even in model bacterial species, there is a sizeable proportion of such genes, which has fundamental and practical consequences. Here, we constructed a complete collection of defined mutants in protein-coding genes – named NeMeSys 2.0 – in the human pathogen Neisseria meningitidis , consisting of individu...

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Literature Corpus work
5a88a2e9-f470-5b06-b255-ad1a28a8fe47
DOI
10.1101/2020.08.12.247981
Open publication

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Construction of a complete set of <i>Neisseria meningitidis</i> defined mutants – the NeMeSys 2.0 collection – and its use for the phenotypic profiling of the genome of an important human pathogenDOI 10.1101/2020.08.12.247981
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