Article

Pangenome evaluation of gene essentiality in <i>Streptococcus pyogenes</i>

2023-08-30

Abstract excerpt

Populations of bacterial pathogens are made of strains that often have variable gene content, termed the pangenome. Variations in the genetic makeup of a single strain can alter bacterial physiology and fitness in response to different environmental stimuli. To define biologically relevant genes within a genome, genome-wide knockout transposon mutant libraries have been used to identify genes essential for surviva...

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Literature Corpus work: 7b56793a-e9a9-5ffe-ae1f-89aa374be901
DOI: 10.1101/2023.08.29.555273

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