Article
NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis.
Genome biology - 1 Jan 2009
Rusniok Christophe, Vallenet David, Floquet Stéphanie, Ewles Helen, Mouzé-Soulama Coralie, Brown Daniel, Lajus Aurélie, Buchrieser Carmen, Médigue Claudine, Glaser Philippe, Pelicic Vladimir
Abstract excerpt
BACKGROUND: Genome sequences, now available for most pathogens, hold promise for the rational design of new therapies. However, biological resources for genome-scale identification of gene function (notably genes involved in pathogenesis) and/or genes essential for cell viability, which are necessary to achieve this goal, are often sorely lacking. This holds true for Neisseria meningitidis, one of the most feared...
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