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Article

Pangenome evaluation of gene essentiality in Streptococcus pyogenes.

Microbiology spectrum - 6 Aug 2024

Jespersen Magnus G, Hayes Andrew J, Tong Steven Y C, Davies Mark R

Abstract excerpt

Bacterial species often consist of strains with variable gene content, collectively referred to as the pangenome. Variations in the genetic makeup of strains can alter bacterial physiology and fitness. To define biologically relevant genes of a genome, genome-wide transposon mutant libraries have been used to identify genes essential for survival or virulence in a given strain. Such phenotypic studies have been...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39012116
DOI: 10.1128/spectrum.03240-23
PMCID: PMC11323703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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