Article

Basal forebrain volume reliably predicts the cortical spread of Alzheimer’s degeneration

2019-06-20

Abstract excerpt

Alzheimer’s disease neuropathology is thought to spread across anatomically and functionally connected brain regions. However, the precise sequence of spread remains ambiguous. The prevailing model posits that Alzheimer’s neurodegeneration starts in the entorhinal cortices, before spreading to temporoparietal cortex. Challenging this model, we previously provided evidence that degeneration within the nucleus basal...

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Literature Corpus work: 59e48755-061a-5d83-9308-6e5ae02ca4a1
DOI: 10.1101/676544

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