Article

Unveiling paths to Alzheimer’s disease: excitation-inhibition ratio shapes hierarchical dynamics

2025-02-25

Abstract excerpt

Alzheimer’s disease is marked by cognitive and memory impairment, with early disruptions in the balance between excitatory and inhibitory neurotransmission, thought to be closely linked to co-occurrent brain changes. The posterior-to-anterior hypothesis posits that functional neurodegeneration begins in critical areas of the default mode network, particularly the hippocampus and posterior cingulate cortex, before...

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Literature Corpus work: aa979dc4-ecdf-5ba2-b852-bdb9762fe9dc
DOI: 10.1101/2025.02.25.25322663

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