Article

Central cholinergic degeneration in prodromal and early manifest Parkinsons disease: relation to cognition, clinical phenotype, and future conversion

2024-12-31

Abstract excerpt

The neuropathological process in Parkinson’s disease (PD) and Lewy body disorders has been shown to extend well beyond the degeneration of the dopaminergic system, affecting other neuromodulatory systems in the brain which play crucial roles in the clinical expression and progression of these disorders. Here, we investigate the role of the macrostructural integrity of the nucleus basalis of Meynert (NbM), the main...

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Literature Corpus work: 7d7e40a1-30b9-50e8-a4c9-df31e3a3371c
DOI: 10.1101/2024.12.31.24319810

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