Article
Leveraging haplotype information in heritability estimation and polygenic prediction
2024-05-01
Abstract excerpt
Polygenic prediction has yet to make a major clinical breakthrough in precision medicine and psychiatry, where the application of polygenic risk scores are expected to improve clinical decision-making. Most widely used approaches for estimating polygenic risk scores are based on summary statistics from external large-scale genome-wide association studies, which relies on assumptions of matching data distributions....
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Identifiers and source
- Literature Corpus work
- 59deeac0-aba5-5f4c-9cb1-6f3fff33a9c5
- DOI
- 10.1101/2024.04.30.24306654