Article

Haplotype based genetic risk estimation for complex diseases

2016-05-25

Abstract excerpt

Genome-wide association studies (GWAS) have uncovered thousands of associations between genetic variants and diseases. Using the same datasets, prediction of disease risk can be attempted. Phase information is an important biological structure that has seldom been used in that setting. We propose here a multi-step machine learning method that aims at using this information. Our method captures local interactions i...

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Literature Corpus work: cb888c4b-1d45-5329-8b00-0e913cbe2878
DOI: 10.7287/peerj.preprints.2074v1

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