Article

The Polygenic Risk Score Knowledge Base: A Centralized Online Repository for Calculating and Contextualizing Polygenic Risk Scores

2021-09-20

Abstract excerpt

<h4>Introduction: </h4> Genome-wide association (GWA) studies identify correlation between genetic variants and phenotypes. GWA findings can be used to calculate polygenic risk scores, which represent the aggregate genetic risk across all associated loci. <h4>Methods: </h4>: We developed a centralized polygenic risk score calculator containing over 2,300 GWA studies from the NHGRI-EBI GWAS Catalog. Polygenic risk...

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Literature Corpus work: 06182098-179f-5782-b317-fa5c4a4d7c90
DOI: 10.21203/rs.3.rs-799235/v1

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