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Integrative analysis of GWAS and co-localisation data suggests novel genes associated with age-related multimorbidity

2022-11-13

Abstract excerpt

Advancing age is the greatest risk factor for developing multiple age-related diseases. When developing therapeutics, using a Geroscience approach to target the shared underlying pathways of ageing, rather than individual diseases, may be an effective way to treat and prevent age-related morbidity while potentially reducing the burden of polypharmacy. We harness the Open Targets Platform and Open Targets Genetics...

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Literature Corpus work
59b6b292-3014-5272-9d89-9111f0785bbf
DOI
10.1101/2022.11.11.22282236
Open publication

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Integrative analysis of GWAS and co-localisation data suggests novel genes associated with age-related multimorbidityDOI 10.1101/2022.11.11.22282236
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