Article

Quantitative Insights into Common and Organ-Specific Aging Gaps via Integrated Multi-Omics Analysis

2026-08-11

Abstract excerpt

<title>Abstract</title> <p>Aging is a complex process marked by both shared and organ-specific declines in function. Here, we leverage data from the UK Biobank (UKB, n=501,623) to disentangle common and organ-specific biological age gaps (BAGs) using 78 physiological and biochemical phenotypes. We refined two metrics, a common BAG (CBAG) and organ-specific BAGs (OSBAGs), that robustly capture global versus locali...

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Literature Corpus work: cbe0e137-f762-540b-8869-581a776dca12
DOI: 10.21203/rs.3.rs-6294979/v1

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