Article

The Genetic Architecture of Biological Age in Nine Human Organ Systems

2023-06-12

Abstract excerpt

Understanding the genetic basis of biological aging in multi-organ systems is vital for elucidating age-related disease mechanisms and identifying therapeutic interventions. This study characterized the genetic architecture of the biological age gap (BAG) across nine human organ systems in 377,028 individuals of European ancestry from the UK Biobank. We discovered 393 genomic loci-BAG pairs (P-value<5×10 -8 ) link...

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Literature Corpus work: 4511b544-7cff-5f15-b33d-74c97a6d426e
DOI: 10.1101/2023.06.08.23291168

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